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Prevalence of antifolate drug resistance markers in in China

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 83-92 doi: 10.1007/s11684-021-0894-x

Abstract: that the antifolate resistance levels of P. vivax parasites were different across China and molecularmarkers could be used to rapidly monitor drug resistance.

Keywords： drug resistance     antifolates     molecular markers     Plasmodium vivax     China    

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Molecular markers and pathogenically targeted therapy in non-small cell lung cancer

Bo PENG BA , Jinnong ZHANG MD , Jamile S. WOODS MD , Wei PENG MD, PhD

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 245-255 doi: 10.1007/s11684-009-0044-3

Abstract: Over the last decade, molecular genetic abnormalities have been described in NSCLC, including chromosomalThese molecular markers in NSCLC demonstrated close associations with the development of lung cancer

Keywords： lung cancer     carcinoma     non-small cell lung cancer     molecular markers     targeted therapy    

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Molecular alterations and clinical relevance in esophageal squamous cell carcinoma

Li Shang, Mingrong Wang

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 401-410 doi: 10.1007/s11684-013-0286-y

Abstract: Molecular classification will be useful for subtyping esophageal tumors or precancerous lesions to improveIn this review, we summarize the findings in investigating the molecular alterations and clinical relevance

Keywords： esophageal squamous cell carcinoma (ESCC)     early detection     molecular classification     molecular markers    

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Identification of molecular markers linked to rice bacterial blight resistance genes from

Jing WANG,Chen CHENG,Yanru ZHOU,Yong YANG,Qiong MEI,Junmin LI,Ye CHENG,Chengqi YAN,Jianping CHEN

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 3,   Pages 260-265 doi: 10.15302/J-FASE-2015070

Abstract: After testing 615 SSR and STS markers covering the 12 rice chromosomes, 186 markers were selected thatMolecular markers linked to the BB resistance genes in Y73 were scanned using the F population and thepolymorphic markers.

Keywords： Oryza meyeriana     bacterial blight resistance gene     genetic population     linkage molecular marker    

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Wheat research and breeding in the new era of a high-quality reference genome

Rudi APPELS

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 3,   Pages 225-232 doi: 10.15302/J-FASE-2019265

Abstract:

The publications of the International Wheat Genome Sequencing Consortium (IWGSC) released in August 2018 are reviewed and placed into the context of developments arising from the availability of the high-quality wheat genome assembly.

Keywords： assembly technology     molecular markers     polyploidy     transcript networks     wheat genome    

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Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis

Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 411-419 doi: 10.1007/s11684-018-0659-3

Abstract: Although many drugs and therapeutic strategies have been developed for rheumatoid arthritis (RA) treatment, numerous patients with RA fail to respond to currently available agents. In this review, we provide an overview of the complexity of this autoimmune disease by showing the rapidly increasing number of genes associated with RA. We then systematically review various factors that have a predictive value (predictors) for the response to different drugs in RA treatment, especially recent advances. These predictors include but are certainly not limited to genetic variations, clinical factors, and demographic factors. However, no clinical application is currently available. This review also describes the challenges in treating patients with RA and the need for personalized medicine. At the end of this review, we discuss possible strategies to enhance the prediction of drug responsiveness in patients with RA.

Keywords： rheumatoid arthritis     gene     clinical markers     therapy    

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The value of epigenetic markers in esophageal cancer

Xiao-Mei ZHANG, Ming-Zhou GUO,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 378-384 doi: 10.1007/s11684-010-0230-3

Abstract: alteration, epigenetic modifications, and in particular DNA methylation, are recognized as a common molecular

Keywords： epigenetics     DNA methylation     esophageal cancer     dysplasia    

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Exploring the diagnosis markers for gallbladder cancer based on clinical data

Lingqiang Zhang,Runchen Miao,Xiude Zhang,Wei Chen,Yanyan Zhou,Ruitao Wang,Ruiyao Zhang,Qing Pang,Xinsen Xu,Chang Liu

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 350-355 doi: 10.1007/s11684-015-0402-2

Abstract:

Presently, no effective markers are available to facilitate gallbladder cancer (GBC) diagnosis.This study aims to explore available markers for GBC diagnosis.curve (AUC), 0.720], ALP (AUC, 0.713), TB (AUC, 0.636), and age (AUC, 0.573) were valuable diagnosis markers

Keywords： marker     gallbladder cancer     diagnosis    

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Effect of renal function and hemodialysis on the serum tumor markers in patients with chronic kidney

YU Xiaofang, XU Xialian, YE Zhibin

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 308-311 doi: 10.1007/s11684-007-0059-6

Abstract: renal failure, whether they have had hemodialysis or not, the specificity of some of the serum tumor markersThe detection of tumor markers is extensively used for the diagnosis of corresponding tumors.It has been recently shown that some tumor markers are higher in patients with chronic kidney diseaseThe effects of renal function and hemodialysis were examined on serum levels of some of the tumor markersNine tumor markers in 37 uremic patients were tested.

Keywords： CKD     non-dialysis     valuable     detection     chronic    

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Clinical study on the related markers of blood coagulation in the patients with ANFH after SARS

WU Lianhua, GAO Chunjin, WANG Guozhong, YANG Lin, HOU Xiaomin, GE Huan, XIA Chengqing, QI Man

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 410-412 doi: 10.1007/s11684-007-0080-9

Abstract: There is no significant difference (>0.05) in those markers between patients and 17 healthy adults.

Keywords： significant difference     partial thromboplastin     coagulation function     femoral     healthy    

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Special issue on “Molecular Sensors and Molecular Logic Gates”

Luling Wu , Tony D. James

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 1-3 doi: 10.1007/s11705-021-2134-y

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Design of bio-oil additives via molecular signature descriptors using a multi-stage computer-aided molecular

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 2,   Pages 168-182 doi: 10.1007/s11705-021-2056-8

Abstract: In this work, computer-aided molecular design tools were developed to design optimal solvents to upgradeAs different property prediction models consist different levels of structural information, molecularDue to the combinatorial nature of higher-order signatures, the complexity of a computer-aided molecular

Keywords： computer-aided molecular design     bio-oil additives     molecular signature descriptor    

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Progress on molecular biomarkers and classification of malignant gliomas

Chuanbao Zhang, Zhaoshi Bao, Wei Zhang, Tao Jiang

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 150-156 doi: 10.1007/s11684-013-0267-1

Abstract: prognostic biomarkers for malignant gliomas have been reported over the last few decades, and these markersGreat efforts have been made to incorporate new information about the molecular landscape of gliomas

Keywords： malignant glioma     molecular biomarker     IDH1     MGMT     molecular classification    

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Molecular classification and molecular targeted therapy of cancer

Miao Xu, Jianyong Shao, Yixin Zeng

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 147-149 doi: 10.1007/s11684-013-0274-2

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Advances in Molecular Electronics: A Brief Review Review

Paven Thomas Mathew, Fengzhou Fang

Engineering 2018, Volume 4, Issue 6,   Pages 760-771 doi: 10.1016/j.eng.2018.11.001

Abstract:

The field of molecular electronics, also known as moletronics, deals with the assembly of molecularNovel research has been performed in developing electrical-equivalent molecular components.Since there is a need to reduce the size of the silicon chip, attaining such technology at the molecularAlthough the experimental verification and modeling of molecular devices present a daunting task, vitalThis article combines an overview of various molecular components, such as molecular transistors, diodes

Keywords： Moletronics     Molecular transistor     Molecular diode     Molecular capacitor     Molecular wire     Graphene    

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Title Author Date Type Operation

Prevalence of antifolate drug resistance markers in in China

Journal Article

Molecular markers and pathogenically targeted therapy in non-small cell lung cancer

Bo PENG BA , Jinnong ZHANG MD , Jamile S. WOODS MD , Wei PENG MD, PhD

Journal Article

Molecular alterations and clinical relevance in esophageal squamous cell carcinoma

Li Shang, Mingrong Wang

Journal Article

Identification of molecular markers linked to rice bacterial blight resistance genes from

Jing WANG,Chen CHENG,Yanru ZHOU,Yong YANG,Qiong MEI,Junmin LI,Ye CHENG,Chengqi YAN,Jianping CHEN

Journal Article

Wheat research and breeding in the new era of a high-quality reference genome

Rudi APPELS

Journal Article

Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis

Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu

Journal Article

The value of epigenetic markers in esophageal cancer

Xiao-Mei ZHANG, Ming-Zhou GUO,

Journal Article

Exploring the diagnosis markers for gallbladder cancer based on clinical data

Lingqiang Zhang,Runchen Miao,Xiude Zhang,Wei Chen,Yanyan Zhou,Ruitao Wang,Ruiyao Zhang,Qing Pang,Xinsen Xu,Chang Liu

Journal Article

Effect of renal function and hemodialysis on the serum tumor markers in patients with chronic kidney

YU Xiaofang, XU Xialian, YE Zhibin

Journal Article

Clinical study on the related markers of blood coagulation in the patients with ANFH after SARS

WU Lianhua, GAO Chunjin, WANG Guozhong, YANG Lin, HOU Xiaomin, GE Huan, XIA Chengqing, QI Man

Journal Article

Special issue on “Molecular Sensors and Molecular Logic Gates”

Luling Wu , Tony D. James

Journal Article

Design of bio-oil additives via molecular signature descriptors using a multi-stage computer-aided molecular

Journal Article

Progress on molecular biomarkers and classification of malignant gliomas

Chuanbao Zhang, Zhaoshi Bao, Wei Zhang, Tao Jiang

Journal Article

Molecular classification and molecular targeted therapy of cancer

Miao Xu, Jianyong Shao, Yixin Zeng

Journal Article

Advances in Molecular Electronics: A Brief Review

Paven Thomas Mathew, Fengzhou Fang

Journal Article